Brand
name: LYNORAL (Ethinyl Estradiol, Estinyl)
Pronounced: Eva-loon
Generic name: Estradiol vaginal ring LYNORAL (Ethinyl Estradiol, Estinyl) (Estradiol, Estrace Vaginal)
Why is LYNORAL (Ethinyl Estradiol, Estinyl) prescribed?
LYNORAL (Ethinyl Estradiol, Estinyl) is an estrogen replacement system for relief of the vaginal
problems that often occur after menopause, including vaginal dryness,
burning, and itching, and difficult or painful intercourse. LYNORAL (Ethinyl Estradiol, Estinyl)
is also prescribed for postmenopausal urinary problems such as difficulty
urinating or urinary urgency.
Most important fact about LYNORAL (Ethinyl Estradiol, Estinyl)
Estrogens increase the risk of cancer in the lining of the uterus,
called the endometrium. Because estrogen replacement therapy is not
advisable if you are in any danger of developing cancer, your doctor
should take a complete medical and family history, and perform a complete
physical exam, before prescribing LYNORAL (Ethinyl Estradiol, Estinyl). It is important to have
regular check-ups (at least once a year) and to report any unusual
vaginal bleeding to your doctor immediately.
LYNORAL (Ethinyl Estradiol, Estinyl) and other estrogen drugs, with or without progesterone, should
not be used to prevent heart disease. Recent studies have confirmed
an increased rate of heart attack, stroke, and dangerous blood clots
among women taking estrogen or estrogen combinations for 5 years. Blood
clots can lead to phlebitis, stroke, heart attack, a loss of blood
supply to the lungs, a blockage in the blood vessels leading to the
eye, and other serious disorders.
How should you use LYNORAL (Ethinyl Estradiol, Estinyl)
(Estradiol, Estrace Vaginal) without prescriptions/rX?
Each LYNORAL (Ethinyl Estradiol, Estinyl) is left in place for 3 months. Press the LYNORAL (Ethinyl Estradiol, Estinyl) into
an oval and insert it as deeply as possible into the upper third of
the vagina. The exact position is unimportant as long as you don't
feel the ring. If the ring causes discomfort, it is probably not far
enough inside.
If the ring slips down into the lower part of the vagina, push it
back up with your finger. If it falls out, rinse it in warm water and
reinsert it. When replacing the ring, simply hook a finger through
it and pull it out.
If you miss a dose...
If the ring is not replaced after 90 days, the dose of estrogen will
gradually decline and your symptoms will return.
Storage instructions...
Store at room temperature.
LYNORAL (Ethinyl Estradiol, Estinyl) (Estradiol, Estrace Vaginal) side effects
Side effects cannot be anticipated. If any develop or change in intensity,
tell your doctor as soon as possible. Only your doctor can determine
if it is safe for you to continue using LYNORAL (Ethinyl Estradiol, Estinyl).
* Side effects may include:
Abdominal pain, arthritis, back pain, flu-like symptoms, headaches, insomnia,
joint pain, nausea, sinus inflammation, upper respiratory tract infections,
vaginal discharge, vaginal discomfort or pain, vaginal inflammation or bleeding,
yeast infection
Why should LYNORAL (Ethinyl Estradiol, Estinyl) not be prescribed?
Do not use LYNORAL (Ethinyl Estradiol, Estinyl) if you have unexplained vaginal bleeding. Also
avoid LYNORAL (Ethinyl Estradiol, Estinyl) if there is a possibility that you are pregnant.
Do not use LYNORAL (Ethinyl Estradiol, Estinyl) if there is any chance that you have breast cancer
or any other cancer stimulated by estrogen. You will also have to avoid
LYNORAL (Ethinyl Estradiol, Estinyl) if it causes an allergic reaction.
Special warnings about LYNORAL (Ethinyl Estradiol, Estinyl)
Estrogen replacement therapy increases the risk of developing cancer
of the lining of the uterus. The risk increases with longer use and
higher doses. Therefore, you should use LYNORAL (Ethinyl Estradiol, Estinyl) for as short a time
and at as low a dose as is necessary to relieve your symptoms. Report
any unusual vaginal bleeding to you doctor immediately.
Using estrogen may also increase the risk of breast cancer, ovarian
cancer, heart attack, stroke, blood clots, and gallbladder disease.
Use estrogen with caution if you have severely low blood levels of
calcium (hypocalcemia).
Tell your doctor if you've ever had liver problems, high cholesterol,
high blood pressure, thyroid problems, or visions problems. Using estrogen
could make these conditions worse.
Estrogens can cause water retention. If you have a condition that
could be affected by this--such as heart or kidney problems--your doctor
will monitor you closely
While using LYNORAL (Ethinyl Estradiol, Estinyl), contact your doctor right away if you develop
any of the following:
Abdominal pain, tenderness, or swelling
Abnormal bleeding from the vagina
Breast lumps
Coughing up blood
Difficulty with speech
Dizziness or faintness
Pains in your chest or calves
Severe headache or vomiting
Sudden shortness of breath
Vision changes
Weakness or numbness of an arm or leg
Yellowing of skin or whites of the eyes (could signal a liver problem)
Any vaginal infection should be cleared up before you begin LYNORAL (Ethinyl Estradiol, Estinyl)
therapy. If an infection develops after you begin, you'll need to remove
the ring during treatment.
Possible food and drug interactions when using LYNORAL (Ethinyl Estradiol, Estinyl)
No interactions have been reported, but LYNORAL (Ethinyl Estradiol, Estinyl) should be removed
during treatment with other vaginally administered drugs.
Special information if you are pregnant or breastfeeding
LYNORAL (Ethinyl Estradiol, Estinyl) must not be used during pregnancy and is not intended for
nursing mothers.
Recommended dosage for LYNORAL (Ethinyl Estradiol, Estinyl)
Insert a new ring every 3 months.
Overdosage
An overdose from LYNORAL (Ethinyl Estradiol, Estinyl) is unlikely. An oral overdose of estrogen
could be expected to cause the symptoms listed below.
