Brand name:
ARCALION
Content Sulbutiamine.
Generic Arcalion, 200 mg tablets
Chemical name: SULBUTIAMINE
Common uses ARCALION without prescriptions
It is a new antiasthenic drug which displays rapid and versatile antiasthenic
efficacy. Symptomatic treatment of functional asthenia and its manifestations
such as fatigue, memory difficulties and intellectual tiredness and
during convalescence from illness and/or infections. Speeds up the
reflexes and recation times in clinical tests. Promotes wakefullness,
and alertness
Directions
Adults: To combat fatigue take two 200mg tablets per day (may vary
from 1-3 tablets daily in single or multiple doses), always with breakfast
or an AM meal, for a period of 20 days. Do not exceed three tablets
at any time as this very powerful substance may cause severe headaches.
Cautions
For women - pregnancy: caution, safety not establised; breast feeding:
use with caution. Old age - Caution, May be given in reduced dose.
Children - Not recommended.
Possible side effects ARCALION
Occasionally: mild agitation in the elderly, allergic skin reactions.
Drug interactions ARCALION
Drug interactions can result in unwanted side effects or prevent a
medicine from doing its job. Some medicines or medical conditions may
interact with this medicine. Inform your doctor or pharmacist of all
prescription and over-the-counter medicine that you are taking.
Description Each tablet contains the following excipients: Maize
starch, sodium carboxymethylcellulose, white beeswax, titanium
dioxide, pregelatinized
maize starch, ethylcellulose, anhydrous glucose, lactose, sunset
yellow FCF, glyceryl mono-oleate, polysorbate 80, polyvidone excipient,
saccharose,
anhydrous colloidal silica, magnesium stearate and talc.
Actions Antiasthenic drug.
Pharmacology: In Animals: Pharmacological studies carried out in
animals, either with acute or chronic administration, have evidenced
the following
actions: Sulbutiamine increases physical resistance to fatigue, neuromuscular
efficiency and learning and memory; and improves the metabolic functions
of the cerebral cortex.
In Man: The activity of sulbutiamine has been studied in functional
asthenia in the course of controlled clinical studies (against placebo
or reference products) using psychometric scales (Middlesex Hospital
Questionnaire, Crocq Scale for the evaluation of nonpsychotic depressive
conditions, Lipman auto-evaluation scale), with statistical analysis
of the results. These studies showed the activity of sulbutiamine
in the symptomatic treatment of functional asthenia.
Pharmacokinetics: Sulbutiamine is rapidly absorbed and the blood
concentration is maximum in 1-2 hrs after oral administration. The
molecule is rapidly
distributed in the whole organism and is eliminated with a biological
half-life of 5 hrs.
The urinary excretion is maximal 2-3 hrs after administration.
Indication Symptomatic treatment of functional asthenia.
Dosage
Adult 2-3 tab daily.
